Characterization of rat vertebrae cortical bone microstructures using confocal Raman microscopy combined to tomography and electron microscopy

The rat vertebrae is a good model to study bone regeneration after implantation of biomaterials used to treat bone loss, a major problem in oral and dental surgery. However, the precise characterization of bone microstructures in the rat vertebrae has not been reported. Therefore, the aim of this study was to achieve the complete analysis of such bone, at different scales, in order to have a clear model of healthy bone for comparison with regenerated bone.

Keywords

Confocal Raman microscopy Cortical bone structure Haversian canals High resolution micro tomography Lamellar bone Mineral density Rat vertebra

Domains

Life Sciences [q-bio]

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Raman Bone Rev1_3.2wm.pdf (1.35 Mo)

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https://hal.science/hal-04785492

Submitted on : Tuesday, November 19, 2024-1:58:02 PM

Last modification on : Monday, November 25, 2024-5:15:14 PM

Dates and versions

hal-04785492 , version 1 (19-11-2024)

Identifiers

HAL Id : hal-04785492 , version 1
DOI : 10.1016/j.aanat.2023.152162
PUBMED : 37774934

Cite

S.A. Shah, H. Salehi, Vincent Cavaillès, F. Fernandez, Frédéric Cuisinier, et al.. Characterization of rat vertebrae cortical bone microstructures using confocal Raman microscopy combined to tomography and electron microscopy. Annals of Anatomy, 2023, 250, pp.152162. ⟨10.1016/j.aanat.2023.152162⟩. ⟨hal-04785492⟩

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